Digestive and Liver Diseases
Liver Diseases
Rafael Esteban Mur
Researchers
Salvador Augustin Recio, Maria Buti Ferret, Lluis Castells Fusté, Laia Chavarria Vilarasau, Juan Ignacio Esteban Mur, Joan Genescà Ferrer, Antonio González Fernández, Jaume Guardia Massó, Maria Martell Pérez-Alcalde, Beatriz Mínguez Rosique, Celia Belen Perales Viejo, Josep Quer Sivila, Francisco Rodríguez Frías, Silvia Sauleda Oliveras, Victor Manuel Vargas Blasco, Lluís Viladomiu Catà
Researchers in training
José Altamirano Gómez, Qian Chen , Maria José Fabrega Fernández, Teresa García Lezana, Maria Homs Riba, Mònica Pons Delgado, Sarai Rodríguez Navarro, David Tabernero Caellas, Meritxell Ventura Cots, Macarena Simón-Talero
Nursing, Technical, and Administrative Staff
Susana Anton Calvo, Maria Blasi Fornaguera, Judit Carbonell Segura, Rosario Casillas Gomez, Damir García Cehic, Monica Higuera Urbano, Leonardo Nieto Aponte, Mª Nieves Palomo Merchan, Immaculada Raurell Saborit, Angeles Rico Blazquez, Maria Eugenia Soria Benito, Francisco Tena Frean, Maria Margarita Torrens Buscató, Manuel Torres Arauz
SUMMARY
The most important aspect of our research in 2014 is the increasing number of international collaborations of our investigators and multicenter clinical trials both academic and commercial.
Dr. Joan Córdoba, clinician from the Internal Medicine- Hepatology Service at Vall d’Hebron University Hospital (HUVH) and outstanding researcher of the Liver Diseases left us at the age of 49 on 27th January. Dr. Córdoba joined the HUVH in 1989 as a doctor in training and continued his experience in the Northwestern University in Chicago for 3 years. He returned to Barcelona as a member of the Internal Medicine- Hepatology Service and became a professor of the Universitat Autònoma de Barcelona. He was a renowned expert of international prestige in the field of hepatic encephalopathy, a notorious clinician and a researcher of tireless dedication. Certainly, he’s been a reference for young doctors and researchers.
PUBLICATIONS
Joan Cordoba Cordona (1964-2014): a dedicated clinician, great scientist, mentor, friend, collaborator, critic…
J Hepatol. 2014 Jun;60(6):1105-7.
PMID: 24959636
Journal:JOURNAL OF HEPATOLOGY
Reference:J Hepatol. 2014 Jun;60(6):1105-7.
Year: 2014
Impact factor: 10,401
Publication type: Paper in international publication
Authors:
Jalan R, Esteban R
Simeprevir with pegylated interferon alfa 2a or 2b plus ribavirin in treatment-naive patients with chronic hepatitis C virus genotype 1 infection (QUEST-2): a randomised, double-blind, placebo-controlled phase 3 trial.
Lancet. 2014 Aug 2;384(9941):414-26. doi: 10.1016/S0140-6736(14)60538-9. Epub 2014 Jun 4.
PMID: 24907224
Journal:LANCET
Reference:Lancet. 2014 Aug 2;384(9941):414-26. doi: 10.1016/S0140-6736(14)60538-9. Epub 2014 Jun 4.
Year: 2014
Impact factor: 39,207
Publication type: Clinical Trials
Authors:
Manns M, Marcellin P, Poordad F, de Araujo ES, Buti M, Horsmans Y, Janczewska E, Villamil F, Scott J, Peeters M, Lenz O, Ouwerkerk-Mahadevan , De La Rosa G, Kalmeijer R, Sinha R, Beumont-Mauviel M
DOI: 10.1016/S0140-6736(14)60538-9
Detection of early portal hypertension with routine data and liver stiffness in patients with asymptomatic liver disease: a prospective study.
J Hepatol. 2014 Mar;60(3):561-9. doi: 10.1016/j.jhep.2013.10.027. Epub 2013 Nov 6.
PMID: 24211744
Journal:JOURNAL OF HEPATOLOGY
Reference:J Hepatol. 2014 Mar;60(3):561-9. doi: 10.1016/j.jhep.2013.10.027. Epub 2013 Nov 6.
Year: 2014
Impact factor: 10,401
Publication type: Paper in international publication
Authors:
Augustin S, Millan L, Gonzalez A, Martell M, Gelabert A, Segarra A, Serres X, Esteban R, Genesca J
DOI: 10.1016/j.jhep.2013.10.027
Characteristics, risk factors and mortality of cirrhotic patients hospitalized for hepatic encephalopathy with and without acute-on-chronic liver failure (ACLF).
J Hepatol. 2014 Feb;60(2):275-81. doi: 10.1016/j.jhep.2013.10.004. Epub 2013 Oct 12.
PMID: 24128414
Journal:JOURNAL OF HEPATOLOGY
Reference:J Hepatol. 2014 Feb;60(2):275-81. doi: 10.1016/j.jhep.2013.10.004. Epub 2013 Oct 12.
Year: 2014
Impact factor: 10,401
Publication type: Paper in international publication
Authors:
Cordoba J, Ventura-Cots M, Simon-Talero M, Amoros A, Pavesi M, Vilstrup H, Angeli P, Domenicali M, Gines P, Bernardi M, Arroyo V
DOI: 10.1016/j.jhep.2013.10.004
Telaprevir twice daily is noninferior to telaprevir every 8 hours for patients with chronic hepatitis C.
Gastroenterology. 2014 Mar;146(3):744-753.e3. doi: 10.1053/j.gastro.2013.11.047. Epub 2013 Dec 4.
PMID: 24316262
Journal:GASTROENTEROLOGY
Reference:Gastroenterology. 2014 Mar;146(3):744-753.e3. doi: 10.1053/j.gastro.2013.11.047. Epub 2013 Dec 4.
Year: 2014
Impact factor: 13,926
Publication type: Clinical Trials
Authors:
Buti M, Agarwal K, Horsmans Y, Sievert W, Janczewska E, Zeuzem S, Nyberg L, Brown RS Jr, Hezode C, Rizzetto M, Parana R, De Meyer S, De Masi R, Luo D, Bertelsen K, Witek J
DOI: 10.1053/j.gastro.2013.11.047
MAIN RESEARCH PROJECTS
ViewIntegrated Approaches for Identifying Molecular Targets in Alcoholic Hepatitis Molecular Subtypes for Targeted Therapies in Alcoholic Hepatittis U01 AA021908-01
PI: Vargas Blasco, Victor Manuel
Funding agency: National Institutes of Health (NIH)
Reference: INTEAM_NIH-NIAAA2013
Funding: 22.500,00 €
Duration: from 2013 to 2018
Prevalencia de las quasispecies mutantes en antígeno de superficie en pacientes con hepatitis crónica B y trasplantados por hepatitis B
PI: Buti Ferret, Maria
Funding agency: Fondo de Investigación Sanitaria
Reference: PI11/01973
Funding: 275.715,44 €
Duration: from 2012 to 2014
Nuevos tratamientos combinados en distintas fases de la cirrosis hepática con hipertensión portal
PI: Genescà Ferrer, Joan
Funding agency: Fondo de Investigación Sanitaria
Reference: PI12/01759
Funding: 85.305,00 €
Duration: from 2013 to 2015
Aplicación de la tecnología de secuenciación masiva para optimizar el coste-efectividad del tratamiento de la hepatitis C (VHC) en la era de los inhibidores de acción directa (DAAs).
PI: Esteban Mur, Juan Ignacio
Funding agency: Fondo de Investigación Sanitaria
Mecanismos de neuromodulación en la hipertensión portal: nuevas posibilidades terapéuticas en la cirrosis hepática.
PI: Martell Pérez-Alcalde, Maria
Funding agency: Fondo de Investigación Sanitaria