Respiratory and Systemic Diseases
Ear, Nose and Throat Disorders
Juan Lorente Guerrero
Researchers
Ana M Garcia Arumí, Juan Piñas Massó, Marc Pellicer Sarasa, Fèlix Pumarola Segura, Javier Vila Martí, David Virós Porcuna, Silvia Naches Solsona, Nuria Ortiz Laredo, Cristina García Vaquero
Collaborations
Santiago Lavín González, Rafaela Cuenca Valera, Josep Pastor Milán, Roser Velarde Nieto, Marta Planelles Basch, Matilde E. Lleonart
SUMMARY
The group conducts research on obstructive sleep apnea syndrome, using canine brachycephalic breeds as an animal model. The main goal of the research is defining which the similarities are and differences between human and animal patients in regard to this disease in order to, if it were the case, be able to use brachycephalic breeds as animal models in the options of treatment of the human disease.
It is necessary to identify markers that enable the prediction of tumoral behavior and responsiveness to different treatments, especially those factors that are predictive of the appearance of metastasis, with the purpose of selecting the patients who can respond most satisfactorily to a certain therapeutic option.
The discovery of novel markers involved in malignant transformation and tumor progression, especially for tumors that lack effective treatment, is an issue of urgent social interest.
Therefore, the identification of new markers in laryngeal tumors of an aggressive nature would allow the discovery of drugs that can cure the disease.
PUBLICATIONS
- Efecto de la presión positiva continua en las vías aéreas y de la cirugía
de las vías aéreas superiores sobre los biomarcadores en condensado de aire exhalado y en suero en pacientes con apnea del sueño Patricia Lloberesa,∗, Sara Sánchez-Vidaurrea,c, Àlex Ferréb,c, María Jesús Cruza,c, Juan Lorente, Gabriel Sampola, Ferran Morella, y Xavier .
Arch Bronconeumol. 2014; 50 (10):422–428