Respiratory and Systemic Diseases
Pneumology
Maria Jesús Cruz, Jaume Ferrer
Researchers
Carles Bravo Masgoret, Maria Luiza De Souza Galvao, Susana Gomez Olles, Javier de Gracia Roldán, Maria Angeles Jiménez Fuentes, Mª Jose Jurado Luque, Patricia Lloberes Canadell, Sergi Martí Beltran, Cèlia Milà Augé, Marc Miravitlles Fernández, Victor Monforte Torres, Ferran Morell Brotad, Antonio Moreno Galdó, Fco. Javier Muñoz Gall, Ma Luisa Navarrete Álvaro, Esther Rodríguez González, Antonio Román Broto, Odile Romero Santo-Tomas, Gabriel Sampol Rubio
Researchers in training
Antonio Álvarez Fernandez, Miriam Barrecheguren Fernández, Cristina Berastegui, Mario Culebras Amigo, Manuel López Meseguer, Iñigo Ojanguren Arranz, Marta Ollé Monge, Mercedes Pallero Castillo, Berta Saez Gimenez, Mònica Sánchez Ortiz, María Guadalupe Silveira, Ana Villar
Nursing, Technical, and Administrative Staff
Daniel Alvarez Simon, Irene Belmonte Mula, Marta Castro de la Visitación, Roser Escobar Fonielles, Sonia Lopez Rodriguez, Emma Lucy Patricia Chang Macchiu, Vicente Ramon Cortina Giner, Cristina Esquinas López, Rosa Lloria Verges, Montserrat Murillo Andres, Nuria Pelaz Garcia d Rios, Thais Pereira Veiga, Maria Antonia Ramon Belmonte, Maria Dolores Untoria Corral
SUMMARY
Among the most important scientific discoveries in 2014 highlights that the group has shown that administration of genetically modified mesenchymal stem cells regenerates lung tissue and stops the inflammatory process in mice with asthma. Dr. Ferran Morell was awarded with one of the “Premios Mejores Ideas 2014”, by Diario Médico, for the discovery of one of the causes of the idiopathic pulmonary fibrosis. The Pneumology Service is one of the coordinators of an international study for the implementation and validation of a diagnostic in vitro tool for Alpha-1 antitrypsin deficiency screening. Currently, the Pneumology service of the Vall d’Hebron Hospital it is one of the hospitals where the largest number of lung transplants are carried out annually, which places it among the leading centers in Europe and the world for this activity. During the last year the group has created the biobank of transplanted patients, providing an important future resource for research in respiratory diseases.
PUBLICATIONS
- Munoz X, Sanchez-Ortiz M, Torres F, Villar A, Morell F, Cruz MJ. Diagnostic yield of specific inhalation challenge in hypersensitivity pneumonitis. Eur Respir J 2014; 44(6):1658-65.
- Ramon MA, Gimeno-Santos E, Ferrer J, Balcells E, Rodriguez E, de Batlle J, Gomez FP, Sauleda J, Ferrer A, Barbera JA, Agusti A, Gea J, Rodriguez-Roisin R, Anto JM, Garcia-Aymerich J. Hospital admissions and exercise capacity decline in patients with COPD. Eur Respir J. 2014 Apr;43(4):1018-27.
- Martinez-Gonzalez I, Cruz MJ, Moreno R, Morell F, Munoz X, Aran JM. Human mesenchymal stem cells resolve airway inflammation, hyperreactivity, and histopathology in a mouse model of occupational asthma. Stem Cells Dev 2014;23(19):2352-63.
- Jose Soler-Cataluna, Alcazar-Navarrete B, Miravitlles M. The concept of control in COPD: a new proposal for optimising therapy. Eur Respir J 2014;44(4):1072-5.
- Lloberes P, Sampol G, Espinel E, Segarra A, Ramon MA, Romero O, Ferrer R, Martinez-Garcia MA, Tovar JL. A randomized controlled study of CPAP effect on plasma aldosterone concentration in patients with resistant hypertension and obstructive sleep apnea. J Hypertens 2014;32(8):1650-7.
MAIN RESEARCH PROJECTS
View- Títol: The impact of air pollution in asthma
IP: Cruz Carmona, María Jesús
Entitat Finançadora: Fondo de Investigación Sanitaria
Referència:CP12/03101
Finançament:120.500,00 €
Duration: from 2013 to 2015 - Títol: Efecto de la suplementación con vitamina D en la prevención de las bronquitis agudas durante el primer año de vida
IP: Moreno Galdó, Antonio
Entitat Finançadora: Ministerio Sanidad Servicios Sociales e Igualdad
Referència:EC11-476
Finançament:148.410,00 €
Duration: from 2012 to 2014 - Títol: Estudio de descubrimiento y validación de potenciales biomarcadores de tolerancia en supervivientes a largo plazo después de un trasplante pulmonar (estudio TOLUNG)
IP: Román Broto, Antonio
Entitat Finançadora: Fondo de Investigación Sanitaria
Referència: PI13/01076
Finançament: 85.910,00 €
Durada: des del 2014 al 2016 - Títol: Fibrosis pulmonar y neumonitis por hipersensibilidad por exposición a antígenos del edredón / almohadón de plumas
IP: Morell Brotad, Ferran
Entitat Finançadora: Fondo de Investigación Sanitaria
Referència: PI13/01377
Finançament: 56.870,00 €
Durada: des del 2014 al 2016 - Titol: Unitat de Recerca de Pneumologia
IP: Morell Brotad, Ferran
Entitat Finançadora: AGAUR
Referència: 2009 SGR 257
Finançament: 54.080,00 €
Durada: des del 2010 al 2014
PATENTS
Title: ENGINEERED STEM CELLS AND THEIR THERAPEUTIC USE
Application number: EP11382362.9
Priority Country: España Priority date: 24 de Noviembre de 2011
Entity holding: IDIBELL / Institut de Recerca Vall d’Hebron / Ciber Enfermedades Respiratorias (CibeRes).