Epidemiology, Pharmacology, New Therapies, Clinical Research

Clinical Pharmacology (FICF)

Joan-Ramon Laporte

Researchers
Cristina Aguilera Martin, Maria Antònia Agustí Escasany, Josep Castel Llobet, María Gloria Cereza García, Immaculada Danés Carreras, Eduard Diogène Fadini, Pili Ferrer Argelés, Albert Figueras Suñé, Immaculada Fuentes Camps, Núria García Dolade, Luisa Ibáñez Mora, Francisco Javier Medel Rebollo, Angeles Mesas Idáñez, Ma Victoria Ribera Canudas, Dolores Rodríguez Cumplido, Mònica Sabaté Gallego, Xavier Vidal Guitart, Maria Elena Ballarín Alins, Eulàlia Pérez Esquirol, Lourdes Vendrell Bosch

Data management, technical and administrative staff
Jose J Barroso Garcia, Montserrat Perez Gonzalez, Ramón Puig Tressera

Researchers in training
Mónica Tarapues, Maria Lujan Iavecchia, Ahmad Safiya

SUMMARY

The Generalitat de Catalunya renewed our recognition of the Fundació Institut Català de Farmacologia as a Consolidated Research Group for the period 2014-2016.

In 2014, six papers from the PROTECT project have been published (four led by members of our group) in peer reviewed journals, focusing on sources of data on out of hospital and inhospital consumption of medicines in Europe, and the utilization of antiepileptic and respiratory medicines. The inventory of European Drug Consumption databases has also been updated by FICF researchers. A study on the perioperative management of antithrombotic therapy has been completed and the preliminary results have been presented in an international congress. The results of a multicentre prospective study on the outcomes of off-label drug use in hospitals have been published.

The relationships with the European networks of drug utilization EuroDURG and PIPERSKA have been strengthened. Members of the group have authored several chapters of an European textbook on drug utilization methods.

PUBLICATIONS

Total 11.
Impact Factor 30.128
Average I.F. 2.739

  • Tarapues M, Cereza G, Arellano AL, Montané E, Figueras A. Serious QT interval prolongation with ranolazine and amiodarone. Int J Cardiol 2014;172:e60-61
  • Danés I, Agustí A, Vallano A, Alerany C, Martínez J, Bosch JA, Ferrer A, Gratacós L, Pérez A, Olmo M, Cano Marron SM, Valderrama A, Bonafont X. Outcomes of off-label drug uses in hospitals: a multicentric prospective study. Eur J Clin Pharmacol 2014;70:1385-93
  • San José A, Agustí A, Vidal X, Formiga F, López-Soto A, Fernández-Moyano A, García J, Ramírez-Duque N, Torres OH, Barbé J, on behalf of potentially inappropriate prescription in older patients in Spain (PIPOPS) investigators‟ project. Inappropriate prescribing to older patients admitted to hospital: a omparison of different tools of misprescribing and underprescribing. Eur J Intern Med 2014;25:710-16.
  • Molina I, Gómez J, Salvador F, Treviño B, Sulleiro E, Serre N, Pou D, Roure S, Cabezos J, Valerio Ll, Blanco-Grau A, Sánchez-Montalvá A, Vidal X, Pahissa A. Randomized trial of posaconazole and benznidazole for chronic Chagas‟ disease. N Engl J Med 2014;370:1899-908.
  • Ferrer P, Ballarín E, Sabaté M, Vidal X, Rottenkolber M, Amelio J, Hasford J, Schmiedl S, Ibáñez L. Antiepileptic drugs and suicide: a systematic review of adverse effects. Neuroepidemiology 2014;42:107-20.

 

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MAIN RESEARCH PROJECTS

  • PI: Agustí Escasany, Maria Antònia
    Abordaje perioperatorio de los pacientes tratados con fármacos antitrombóticos: resultados clínicos y económicos tras la implementación de un protocolo asistencial.
    Funding Agency: Ministerio de Sanidad
    Reference: EC11-495
    Funding: 61,710€
    From: 2011 to: 2013
  • PI: Ibáñez Mora, Luisa
    Caracterización de perfiles proteómicos predictivos de hepatotoxicidad asociada a medicamentos antituberculosos: un estudio exploratorio
    Funding Agency: Fondo de Investigación Sanitaria
    Reference: EC08/00250
    Funding: 150,645.00 €
    From: 2009 to: 2012
  • PI: Laporte Roselló, Joan-Ramon
    Fundació Institut Català de Farmacologia
    Funding Agency: AGAUR
    Reference: 20149 SGR 766
    Funding: 21,000 €
    From: 2014 to: 2016
  • PI: Ibáñez Mora, Luisa
    Determinantes genéticos en la agranulocitosis asociada al uso de medicamentos: un estudio de casos y controles
    Funding Agency: Fondo de Investigación Sanitaria
    Reference: PI10/02632
    Funding: 182,710.00 €
    From: 2011 to: 2013

 

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